Journal
NATURE NEUROSCIENCE
Volume 8, Issue 12, Pages 1660-1662Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn1589
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Funding
- NINDS NIH HHS [R01 NS049488] Funding Source: Medline
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Odors detected by the vomeronasal organ or the main olfactory epithelium (MOE) trigger social behaviors in many animals. It is unknown whether MOE neurons detect cues that initiate mating or aggression. We demonstrate that mice lacking functional CNGA2 ( cyclic nucleotide - gated channel alpha 2), which is required for odor-evoked MOE signaling, fail to mate or fight, suggesting a broad and essential role for the MOE in regulating these behaviors.
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