Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 43, Issue 12, Pages 6171-6175Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.43.12.6171-6175.2005
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Phylogenetic analysis of 45 enterovirus 71 (EV71) isolates for 6 years in Yamagata, Japan, clarified that the annual outbreak of hand-foot-and-mouth disease was due to four genetically distinct subgenogroups, including a novel B5. Our results suggest that the importation of EV71 from surrounding countries has had a major epidemiological impact on the local community used in our study.
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