Journal
INFECTION AND IMMUNITY
Volume 73, Issue 12, Pages 8407-8410Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.73.12.8407-8410.2005
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Funding
- NIAID NIH HHS [R01 AI019844, R37 AI019844, AI19844] Funding Source: Medline
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In vitro, Clostridium perfringens enterotoxin (CPE) binds to human ileal epithelium and induces morphological damage concurrently with reduced short-circuit current, transepithelial resistance, and net water absorption. CPE also binds to the human colon in vitro but causes only slight morphological and transport changes that are not statistically significant.
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