Journal
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY
Volume 105, Issue 1, Pages 65-69Publisher
MANEY PUBLISHING
DOI: 10.1179/136485910X12851868780342
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Funding
- Beijing New Century Millions of Talents Project [B2006003]
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As the information available on the treatment of angiostrongyliasis with a combination of albendazole and dexamethasone is limited, the efficacy of such therapy was assessed using data collected during the 2006 outbreak of angiostrongyliasis in Beijing. In a retrospective and controlled study, 35 patients treated with albendazole-dexamethasone (given 20 mg albendazole/kg and 3 mg dexamethasone daily for 7 days) were compared with 34 controls who were treated only symptomatically (with acetaminophen or other drugs). Compared with the controls, the patients given the combination were less likely to have headaches after 7 days (P=0.038), tended to have headaches that cleared quicker (P=0.010), and received fewer doses of acetaminophen (P=0.036). Since no serious adverse effects were observed, a 1-week treatment with a combination of albendazole and dexamethasone appears both safe and beneficial in the treatment of angiostrongyliasis.
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