4.6 Review

Dendritic cells: Tools and targets for transplant tolerance

Journal

AMERICAN JOURNAL OF TRANSPLANTATION
Volume 5, Issue 12, Pages 2807-2813

Publisher

WILEY
DOI: 10.1111/j.1600-6143.2005.01116.x

Keywords

antigen presentation; dendritic cells; regulatory T cells

Funding

  1. NIAID NIH HHS [AI055794, AI52052, AI51698, AI60994] Funding Source: Medline
  2. NIDDK NIH HHS [DK4545] Funding Source: Medline

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Our knowledge of the role of dendritic cells (DC) in the generation and maintenance of T-cell tolerance has expanded rapidly and is now a key area of research in basic and applied DC biology. This minireview highlights recent developments in the field that are leading to new avenues for exploiting DC in the promotion of transplant tolerance.

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