4.6 Article

Synthesis of reduced xanthatin derivatives and in vitro evaluation of their antifungal activity

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Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14756360500213231

Keywords

antifungal agents; sesquiterpenic lactone; xanthanolide; Candida glabrata; Candida albicans; Aspergillus fumigatus

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The synthesis of new xanthanolide derivatives is reported starting from xanthatin, a sesquiterpenic lactone isolated from Xanthium macrocarpum ( Asteraceae). In vitro evaluation of their antifungal activity has been investigated.

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