Journal
JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS
Volume 10, Issue 3, Pages 180-183Publisher
NATURE PUBLISHING GROUP
DOI: 10.1111/j.1087-0024.2005.10101.x
Keywords
hair follicle; plasticity; stem cells; tissue engineering; dermal papilla; dermal sheath
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Funding
- Biotechnology and Biological Sciences Research Council [BBS/B/14558] Funding Source: Medline
- Biotechnology and Biological Sciences Research Council [BBS/B/14558] Funding Source: researchfish
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The dermal components of the hair follicle exhibit a number of stem cell properties, including regenerative potential, roles in wound healing and the ability to produce a functional dermis. Here we examine the stem cell phenomenon of plasticity, focusing on recent observations of in vitro plasticity of dermal papilla and sheath cells, including previously unpublished data of neuronal-like differentiation. We then briefly address the implications of the stem cell potential of hair follicle dermal cells for the field of tissue engineering.
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