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Archaeal chromation proteins: different structures but common function?

Journal

CURRENT OPINION IN MICROBIOLOGY
Volume 8, Issue 6, Pages 656-661

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2005.10.007

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Chromatin proteins promote chromosome flexibility in vivo, maintaining a compact yet decondensed template that permits polymerase accessibility. All Archaea have at least two types of chromatin proteins, and diversity in the chromatin protein population appears to prevent polymerization of a single type of protein. Of the numerous chromatin proteins that have been described in Archaea, only two - histories and Alba homologs - are present in all archaeal phyla. Although their structures and complexes with DNA have no similarities, their functions probably overlap as mutants that lack single chromatin proteins are viable.

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