Journal
AMERICAN JOURNAL OF PSYCHIATRY
Volume 162, Issue 12, Pages 2384-2386Publisher
AMER PSYCHIATRIC PUBLISHING, INC
DOI: 10.1176/appi.ajp.162.12.2384
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- Wellcome Trust Funding Source: Medline
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Objective: Patients with schizophrenia experiencing delusions and hallucinations can misattribute their own actions to an external source. The authors test the hypothesis that patients with schizophrenia have defects in their ability to predict the sensory consequences of their actions. Method: The authors measured sensory attenuation of self-produced stimuli by patients with schizophrenia and by healthy subjects. Results: Patients with schizophrenia demonstrated significantly less sensory attenuation than healthy subjects. Conclusions: Patients with a diagnosis of schizophrenia have a dysfunction in their predictive mechanisms.
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