Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 49, Issue 12, Pages 5127-5128Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.49.12.5127-5128.2005
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Funding
- Wellcome Trust Funding Source: Medline
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By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in characterizing the disposition of slowly eliminated antimalarial drugs.
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