Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 7, Issue 6, Pages 843-845Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020310001653318
Keywords
microbial transformation; fraxinellone; dasycarpol; fraxinigerllone; Aspergillus niger
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Microbial transformation of fraxinellone (1) by Aspergillus niger (AS 3.421) has been carried out. Two converted products, dasycarpol (2) and a new compound fraxinigerllone (3) were obtained. Their structures have been identified on the basis of spectroscopic methods. Dasycarpol shows moderate inhibitory activity on lung cancer cell line A549.
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