4.4 Article

Total synthesis of beauveriolide I

Journal

TETRAHEDRON LETTERS
Volume 46, Issue 49, Pages 8579-8581

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.09.188

Keywords

ACAT inhibitor; beauveriolide I; total synthesis

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The first total synthesis of beauveriolide I (1a), a selective ACAT inhibitor, is described. The key steps in this synthesis involved a diastercoselective aldol condensation sequence and a macrocyclization. (c) 2005 Elsevier Ltd. All rights reserved.

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