Journal
ORGANIC LETTERS
Volume 7, Issue 25, Pages 5737-5739Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol052512u
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A stereoselective total synthesis of the visual pigment A2E has been achieved with use of palladium-catalyzed cross-coupling reactions in all key steps: a regioselective Suzuki or Negishi coupling of 2,4-dibromopyridine, a Sonogashira reaction, and a double Stille cross-coupling to complete the bispolyenyl skeleton.
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