Journal
NEUROLOGY
Volume 65, Issue 11, Pages 1817-1819Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.wnl.0000187068.92184.63
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Funding
- NCRR NIH HHS [5 M01 RR-00079] Funding Source: Medline
- NIA NIH HHS [AG10123, AG17586, P50-AG16753, P01 AG019724, P01-AG19724] Funding Source: Medline
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Pedigrees from 269 patients with frontotemporal lobar degeneration (FTLD), including frontotemporal dementia (FTD), FTD with ALS (FTD/ALS), progressive nonfluent aphasia, semantic dementia (SD), corticobasal degeneration, and progressive supranuclear palsy were analyzed to determine the degree of heritability of these disorders. FTD/ ALS was the most and SD the least heritable subtype. FTLD syndromes appear to have different etiologies and recurrence risks.
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