4.5 Article

Estrogen receptor β selective ligands:: Discovery and SAR of novel heterocyclic ligands

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 15, Issue 24, Pages 5562-5566

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.08.010

Keywords

estrogen receptor; ER beta selective ligands

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A series of ligands with varying heterocyclic cores and substituents that display a range of selectivity's (up to > 100x) for ER-beta over ER-alpha are reported. (c) 2005 Elsevier Ltd. All rights reserved.

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