Adsorption of amoxicillin on chitosan beads:: Kinetics, equilibrium and validation of finite bath models

The kinetics and equilibrium of amoxicillin adsorption on chitosan beads have been determined in batch studies. The fit to experimental equilibrium data indicates that the isotherm for this system can be considered of Langmuir type. Two mathematical models proposed in the literature were used to describe the adsorption kinetic. The validation of the models allowed optimizing mass transfer parameters, that describe the phenomena of internal diffusion and external convection on chitosan beads, as well as determining the kinetic rate constant. (c) 2005 Elsevier B.V. All rights reserved.