4.8 Article

A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells

Publisher

NATL ACAD SCIENCES
DOI: 10.1073/pnas.0509455102

Keywords

alternative transcripts; development; serial analysis of gene expression

Funding

  1. NCI NIH HHS [N01-C0-012400] Funding Source: Medline
  2. PHS HHS [N01-C0-12400] Funding Source: Medline

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We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing gene data sets and evidence for the existence of approximate to 24,000 previously undescribed genomic loci. The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci.

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