4.4 Article

A simple and efficient one step synthesis of 1,3,4-oxadiazoles utilizing polymer-supported reagents and microwave heating

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 1, Pages 105-108

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.10.131

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1,3,4-Oxadiazoles can be rapidly and efficiently synthesized from a variety of carboxylic acids and acid hydrazides in one simple step. The use of commercially available PS-PPh3 resin combined with microwave heating delivered the product 1,3,4-oxadiazoles in high yields and purities. (c) 2005 Elsevier Ltd. All rights reserved.

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