4.4 Article

Phosphine-catalyzed one-pot synthesis of cyclopentenes from electron-deficient allene, malononitrile and aromatic aldehydes

Journal

TETRAHEDRON
Volume 62, Issue 2-3, Pages 457-460

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2005.09.100

Keywords

phosphine; cyclopentenes; malononitrile; aromatic aldehydes; electron-deficient allene

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A three component reaction of aryl aldehydes and malononitrile with ethyl 2,3-butadienoate catalyzed by triphenylphosphine has been developed. The reaction furnishes highly functionalized cyclopentenes in moderate to good yields in a one-pot process. (c) 2005 Elsevier Ltd. All rights reserved.

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