Journal
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
Volume 364, Issue 1838, Pages 249-261Publisher
ROYAL SOC
DOI: 10.1098/rsta.2005.1687
Keywords
supercritical carbon dioxide; polymer scaffold foam
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Funding
- Engineering and Physical Sciences Research Council [GR/S27269/01] Funding Source: researchfish
- Wellcome Trust [073913] Funding Source: Medline
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This paper describes recent progress made in the use of high pressure or supercritical fluids to process polymers into three-dimensional tissue engineering scaffolds. Three current examples are highlighted: foaming of acrylates for use in cartilage tissue engineering; plasticization and encapsulation of bioactive species into biodegradable polyesters for bone tissue engineering; and a novel laser sintering process used to fabricate three-dimensional biodegradable polyester structures from particles prepared via a supercritical route.
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