Journal
TOXICOLOGY
Volume 217, Issue 2-3, Pages 81-90Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.tox.2005.10.001
Keywords
bisphenol A; metabolism; biodegradation; toxic activity; estrogenic activity
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Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane; CAS Registry No. 80-05-7) is one of endocrine disruptors and is made by combining acetone and phenol. BPA can be metabolized by extensive organisms. In this review these BPA biodegradations or metabolisms by many organisms from microorganisms to mammals were referred. Though the metabolites of BPA can enhance estrogenicity or toxicity, generally, BPA metabolism by organisms leads to detoxication of BPA. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
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