Journal
SYNTHESIS-STUTTGART
Volume -, Issue 2, Pages 224-226Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2005-918507
Keywords
thioamides; nitriles; phosphorus pentasulfide; phosphorodithioates; addition reactions
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A simple, efficient, and new method has been developed for the synthesis of thioamides from nitriles. The reaction of a variety of aromatic and aliphatic nitriles in the presence of phosphorus pentasulfide afforded the corresponding thioamides in high yields. This method is easy, rapid, and high-yielding for the synthesis of thioamides from nitriles.
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