4.8 Article

A ring-closing yne-carbonyl metathesis of ynamides

Journal

ORGANIC LETTERS
Volume 8, Issue 2, Pages 231-234

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol052487s

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Funding

  1. NIGMS NIH HHS [GM066055] Funding Source: Medline

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An acid-catalyzed ring-closing ynamide-carbonyl metathesis is described here. This hetero RCM methodology is applicable to the construction of carbocycles as well as heterocycles such as chromenes, quinolizidines, indolizidines, and pyrrolizidines.

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