4.7 Article

Practical method for transforming alkynes into α-diketones

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 71, Issue 2, Pages 826-828

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo051793g

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[GRAPHICS] Oxidation of alkynes to alpha-dicarbonyl derivatives through a convenient one-pot procedure via a Bronsted acid-promoted hydration and a DMSO-based oxidation sequence has been achieved in high yields. The scope and limitations of the reaction have also been investigated.

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