Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 8, Issue 1, Pages 1-5Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsami.5b09079
Keywords
clenbuterol; colorimetric detection; gold nanoparticle; excellent selectivity; high sensitivity
Funding
- NSFC [21571110, 31128007]
- Chinese Academy of Sciences [KFJ-EW-STS-016]
- Ningbo Municipality [2014B82010, 2015B11002]
- Hundred Talents Program of Chinese Academy of Sciences [2010-735]
- Zhejiang Provincial Natural Science Foundation of China [R5110230]
- Ningbo Foundation [2014C50037, 2014A610106]
- K. C. Wong Magna Fund in Ningbo University
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Demonstrated was a simple visual and rapid colorimetric sensor for detection of clenbuterol (CLB) based on gold nanoparticles (AuNPs) modified with cysteamine (CA) and characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), UV-vis. The solution color from red to blue gray with increasing clenbuterol concentration resulted from the aggregation of AuNPs. The detection limit of clenbuterol is 50 nM by naked eyes. The selectivity of CA-AuNPs detection system for clenbuterol is excellent compared with other interferents in food. This sensor has been successfully applied to detect clenbuterol in real blood sample.
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