Journal
NATURE REVIEWS NEUROSCIENCE
Volume 7, Issue 2, Pages 115-125Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn1844
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Funding
- NINDS NIH HHS [R01 NS041564-06, R01 NS041564] Funding Source: Medline
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Ca2+ signals have profound and varied effects on growth cone motility and guidance. Modulation of Ca2+ influx and release from stores by guidance cues shapes Ca2+ signals, which determine the activation of downstream targets. Although the precise molecular mechanisms that underlie distinct Ca2+-mediated effects on growth cone behaviours remain unclear, recent studies have identified important players in both the regulation and targets of Ca2+ signals in growth cones.
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