Journal
JOURNAL OF CUTANEOUS PATHOLOGY
Volume 33, Issue -, Pages 10-17Publisher
WILEY
DOI: 10.1111/j.0303-6987.2006.00507.x
Keywords
-
Categories
Funding
- NCI NIH HHS [P50-CA93683] Funding Source: Medline
Ask authors/readers for more resources
CD30+ cutaneous lymphoproliferative disorders include lymphomatoid papulosis (LyP) and anaplastic large cell lymphoma (ALCL). LyP is associated with development of lymphoma in nearly 20% of patients. Herein is reviewed the clonal relationship of LyP to malignant lymphoma, the concept of a common stem cell for LyP and associated lymphomas, and the role of genetic instability in lymphomagenesis. The possible role of the CD30+ cell as a regulatory T-cell is introduced and a model for progression of LyP to ALCL is illustrated.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available