4.2 Article

A large family with Charcot-Marie-Tooth Type 1A and Type 2 diabetes mellitus

Journal

INTERNATIONAL JOURNAL OF NEUROSCIENCE
Volume 116, Issue 2, Pages 103-114

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/00207450500341431

Keywords

Charcot-Marie-Tooth disease Type 1A; duplication at chromosome 17p11.2; Type 2 diabetes mellitus

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Charcot-Marie-Tooth (CMT) disease is a hereditary demyelinating peripheral neuropathy, and CMT Type 1A is the most common form. In most cases, CMT1A is usually caused by duplication at chromosome 17p11.2-12. Type 2 diabetes mellitus ( Type 2 DM) is a common metabolic disorder, characterized by chronic hyperglycemia that can be associated with micro- and/or macrovascular.

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