Journal
SYNLETT
Volume -, Issue 2, Pages 263-266Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2006-926227
Keywords
4H-benzo[b]pyrans; 4H-chromene; aqueous media; (S)-proline; Knoevenagel-cyclocondensation reaction
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(S)-Proline has been used as a mild, efficient and neutral catalyst for synthesis of various 4H-benzo[b]pyran derivatives via a one-pot three-component condensation of aromatic aldehydes, active methylene compounds, and dimedone in aqueous media. This method offers the advantages of proceeding and neutral and mild conditions, giving high to excellent yields of the products and simple workup.
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