Journal
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
Volume 12, Issue 1, Pages 37-40Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.rhu.0000200420.67262.04
Keywords
-
Categories
Funding
- NCRR NIH HHS [M01 RR00052] Funding Source: Medline
- NIAMS NIH HHS [AR 43737] Funding Source: Medline
Ask authors/readers for more resources
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease most frequently presenting as photosensitive rash, polyarthritis, or renal disease. It represents the tip of the iceberg of autoimmunity. Positive antinuclear antibody (ANA) occurs in 10% or more of normal young women (but 96% or more of patients with SLE). Localized autoimmune disorders such as autoimmune thyroid disease, juvenile-onset diabetes mellitus, Sjogren syndrome, and others Occur in approximately 10% of the population. Systemic autoimmunity, however, is rarer. Undifferentiated connective tissue disease (UCTD) may occur in as many as 5% of Women, but usually does not progress over time into true SLE. SLE remains one of the most fascinating and enigmatic of the autoimmune diseases and a constant challenge to rheumatologists and other specialists.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available