Journal
TOXICON
Volume 47, Issue 2, Pages 156-162Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.toxicon.2005.10.013
Keywords
cylindrospermopsin; Aphanizomenon flos-aquae; Cyanobacteria; Germany
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Three single-filament isolates of Aphanizomenon flos-aquae from two German lakes were found to produce remarkable amounts of the cyanobacterial hepatotoxin cylindrospermopsin (CYN). CYN-synthesis of the strains were evidenced both by LC-MS/MS analysis and detection of PCR products of gene fragments which are implicated in the biosynthesis of the toxin. The strains contain CYN in the range of 2.3-6.6 mg g(-1) of cellular dry weight. To our knowledge this is the first report of CYN in A. flos-aquae. (c) 2005 Elsevier Ltd. All rights reserved.
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