4.5 Article

Walking with myosin V

Journal

CURRENT OPINION IN CELL BIOLOGY
Volume 18, Issue 1, Pages 68-73

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2005.12.014

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Funding

  1. Medical Research Council [MC_U117570593] Funding Source: researchfish
  2. MRC [MC_U117570593] Funding Source: UKRI
  3. Medical Research Council [MC_U117570593] Funding Source: Medline

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The cytoplasm of cells is teeming with vesicles and other cargo that are moving along tracks of microtubules or actin filaments, powered by myosins, kinesins and dyneins. Myosin V has been implicated in several types of intracellular transport. The mechanism by which myosin V moves processively along actin filaments has been the subject of many biophysical and biochemical studies and a consensus is starting to emerge about how this minute molecular motor operates.

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