Journal
OPTICS LETTERS
Volume 31, Issue 3, Pages 362-364Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.31.000362
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Funding
- NCI NIH HHS [R01 CA103769-02, R33 CA110130-02, R33 CA110130, R01 CA103769] Funding Source: Medline
- NHLBI NIH HHS [R01 HL076398-02, R01 HL076398, R01 HL070039, R01 HL70039, R01 HL070039-02] Funding Source: Medline
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A novel optical frequency-domain imaging system is demonstrated that employs a passive optical demodulation circuit and a chirped digital acquisition clock derived from a voltage-controlled oscillator. The demodulation circuit allows the separation of signals from positive and negative depths to better than 50 dB, thereby eliminating depth degeneracy and doubling the imaging depth range. Our system design is compatible with dual-balanced and polarization-diverse detection, important techniques in the practical biomedical application of optical frequency-domain imaging. (c) 2006 Optical Society of America.
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