Journal
MEDICAL MYCOLOGY
Volume 44, Issue 1, Pages 33-39Publisher
OXFORD UNIV PRESS
DOI: 10.1080/13693780500179678
Keywords
Scedosporium; Pseudallescheria; Polycytella; mycetoma; rDNA sequence
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Funding
- NERC [bas010015] Funding Source: UKRI
- Natural Environment Research Council [bas010015] Funding Source: researchfish
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PCR amplification and sequencing of two separate regions of the nuclear ribosomal repeat region revealed that Polycytella hominis, a hyphomycete isolated from a human case of mycetoma, was genetically indistinguishable from Scedosporium apiospermum (the anamorph of Pseudallescheria boydii). These organisms also exhibited remarkably similar susceptibility profiles to common antifungal agents. P. hominis is thus likely to be a mutant of S. apiospermum showing abnormalities of sporulation, for which a possible mechanism is discussed. Polycytella hominis should thus be regarded as a synonym of Scedosporium apiospermum.
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