Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 25, Issue 2, Pages 143-154Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2005.05.008
Keywords
biological sample; MIP; MISPE; molecularly imprinted polymer; molecularly imprinted solid-phase extraction; solid-phase extraction; SPE; water sample
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In this paper, we review the current state of the art in the use of molecularly imprinted polymers (MIPs) as selective materials in molecularly imprinted solid-phase extraction (MISPE). The application of these synthetic polymers as sorbents allows not only pre-concentration and cleaning of the sample but also selective extraction of the target analyte, which is important, particularly when the sample is complex and impurities can interfere with quantification. We therefore discuss the application of MISPE to compounds from complex matrices, such as environmental and biological samples. (C) 2005 Elsevier Ltd. All rights reserved.
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