Journal
SCIENCE
Volume 311, Issue 5761, Pages 622-627Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1114397
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Funding
- NIAID NIH HHS [P01 AI50495] Funding Source: Medline
- NIEHS NIH HHS [R01 ES12053, R0-1 ES10553, R01 ES013432] Funding Source: Medline
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Nanomaterials are engineered structures with at least one dimension of 100 nanometers or less. These materials are increasingly being used for commercial purposes such as filters, opacifiers, catalysts, semiconductors, cosmetics, microelectronics, and drug carriers. Materials in this size range may approach the length scale at which some specific physical or chemical interactions with their environment can occur. As a result, their properties differ substantially from those bulk materials of the same composition, allowing them to perform exceptional feats of conductivity, reactivity, and optical sensitivity. Possible undesirable results of these capabilities are harmful interactions with biological systems and the environment, with the potential to generate toxicity. The establishment of principles and test procedures to ensure safe manufacture and use of nanomaterials in the marketplace is urgently required and achievable.
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