Journal
TETRAHEDRON
Volume 62, Issue 7, Pages 1527-1535Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2005.11.011
Keywords
3,3-Di(heteroaryl)indolin-2-one; CAN; indole; isalin
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Ceric ammonium nitrate efficiently catalyzes the reaction of isatin with indoles under sonic waves to afford symmetrical 3,3-di(indolyl)indolin-2-ones in excellent yields, as well as the reaction of 3-hydroxy-3-indolylindolin-2-ones with indoles, pyrrole to afford the corresponding adducts in excellent yields, which provides an efficient route to the synthesis of symmetrical and unsymmetrical 3,3-di(indolyl)indolin-2-one derivatives, respectively. (c) 2005 Elsevier Ltd. All rights reserved.
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