4.4 Article

Preparation of the neolignan natural product grossamide by a continuous-flow process

Journal

SYNLETT
Volume -, Issue 3, Pages 427-430

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/S-2006-926244

Keywords

poly mer-supported reagents; enzymes; flow synthesis; natural products

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This article describes the first enantioselective total synthesis of 2-aryl-2,3-dihydro-3-beiizofurancarboxyamide neolignan, grossamide (1) using a fully automated and scalable flow reactor.

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