4.4 Article

Expeditious synthesis of novel NK1 antagonists based on a 1,2,4-trisubstituted cyclohexane

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 8, Pages 1295-1298

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.12.067

Keywords

NK1; asymmetric synthesis; triazole; alpha-arylation

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A stereoselective asymmetric route to novel potent NK1 antagonists based on a 1.2,4-trisubstituted cyclohexane core is discussed. (c) 2005 Elsevier Ltd. All rights reserved.

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