Journal
JOURNAL OF CELL BIOLOGY
Volume 172, Issue 5, Pages 645-650Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.200512057
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Funding
- MRC [G0000107, MC_U105178783] Funding Source: UKRI
- Medical Research Council [MC_U105178783, G0000107] Funding Source: Medline
- NIGMS NIH HHS [R01 GM068029, GM68029, R01 GM067226, GM67226] Funding Source: Medline
- Medical Research Council [MC_U105178783, G0000107] Funding Source: researchfish
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The Ras superfamily is comprised of at least four large families of regulatory guanosine triphosphate-binding proteins, including the Arfs. The Arf family includes three different groups of proteins: the Arfs, Arf-like (Arls), and SARs. Several Arf family members have been very highly conserved throughout eukaryotic evolution and have orthologues in evolutionally diverse species. The different means by which Arf family members have been identified have resulted in an inconsistent and confusing array of names. This confusion is further compounded by differences in nomenclature between different species. We propose a more consistent nomenclature for the human members of the Arf family that may also serve as a guide for nomenclature in other species.
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