Related references
Note: Only part of the references are listed.Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model
Odile Gabay et al.
ARTHRITIS AND RHEUMATISM (2013)
The overexpression of SIRT1 inhibited osteoarthritic gene expression changes induced by interleukin-1β in human chondrocytes
Takehiko Matsushita et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes
M. -H. Moon et al.
OSTEOARTHRITIS AND CARTILAGE (2013)
Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice
Odile Gabay et al.
ANNALS OF THE RHEUMATIC DISEASES (2012)
75-kd sirtuin 1 blocks tumor necrosis factor a-mediated apoptosis in human osteoarthritic chondrocytes
Hanna Oppenheimer et al.
ARTHRITIS AND RHEUMATISM (2012)
Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity
Sangkyu Kim et al.
BIOGERONTOLOGY (2012)
Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity
Lei Ming et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Age-associated decrease of SIRT1 expression in rat hippocampus Prevention by late onset caloric restriction
Ana Quintas et al.
EXPERIMENTAL GERONTOLOGY (2012)
Tumor Necrosis Factor α-Mediated Cleavage and Inactivation of SirT1 in Human Osteoarthritic Chondrocytes
Mona Dvir-Ginzberg et al.
ARTHRITIS AND RHEUMATISM (2011)
Sirt1 Is a Regulator of Bone Mass and a Repressor of Sost Encoding for Sclerostin, a Bone Formation Inhibitor
Einav Cohen-Kfir et al.
ENDOCRINOLOGY (2011)
The Reduction of SIRT1 in Livers of Old Mice Leads to Impaired Body Homeostasis and to Inhibition of Liver Proliferation
Jingling Jin et al.
HEPATOLOGY (2011)
Induction of Sirt1 by Mechanical Stretch of Skeletal Muscle through the Early Response Factor EGR1 Triggers an Antioxidative Response
Patricia S. Pardo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc
Jianru Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
SIRT1 Regulation of Wakefulness and Senescence-Like Phenotype in Wake Neurons
Lori Panossian et al.
JOURNAL OF NEUROSCIENCE (2011)
Potential Involvement of SIRT1 in the Pathogenesis of Osteoarthritis Through the Modulation of Chondrocyte Gene Expressions
Norifumi Fujita et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2011)
Sirtuins, Aging, and Medicine
Leonard Guarente
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Mammalian Sirtuins: Biological Insights and Disease Relevance
Marcia C. Haigis et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
SirT1 Enhances Survival of Human Osteoarthritic Chondrocytes by Repressing Protein Tyrosine Phosphatase 1B and Activating the Insulin-like Growth Factor Receptor Pathway
Viktoria Gagarina et al.
ARTHRITIS AND RHEUMATISM (2010)
Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1(+/-) Mice: A Role of Lipid Mobilization and Inflammation
Fen Xu et al.
ENDOCRINOLOGY (2010)
Ionizing Radiation Induces Cellular Senescence of Articular Chondrocytes via Negative Regulation of SIRT1 by p38 Kinase
Eun-Hee Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SIRT1 Regulation of Apoptosis of Human Chondrocytes
Koji Takayama et al.
ARTHRITIS AND RHEUMATISM (2009)
SIRT1 and insulin resistance
Fengxia Liang et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Regulation of Cartilage-specific Gene Expression in Human Chondrocytes by SirT1 and Nicotinamide Phosphoribosyltransferase
Mona Dvir-Ginzberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis
Rui-Hong Wang et al.
MOLECULAR CELL (2008)
NAD+-dependent deacetylation of H4 lysine 16 by class IIIHDACs
A. Vaquero et al.
ONCOGENE (2007)
Aggrecanolysis in human osteoarthritis: confocal localization and biochemical characterization of ADAMTS5 - hyaluronan complexes in articular cartilages
A. Plaas et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Interleukin-1β induced activation of nuclear factor-κb can be inhibited by novel pharmacological agents in osteoarthritis
S. N. Lauder et al.
RHEUMATOLOGY (2007)
SIRT1 promotes DNA repair activity and deacetylation of Ku70
Jaemin Jeong et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2007)
SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice
Hongzhe Li et al.
BREAST CANCER RESEARCH (2007)
Progressive loss of SIRT1 with cell cycle withdrawal
Tsutomu Sasaki et al.
AGING CELL (2006)
Understanding the role of tissue degrading enzymes and their inhibitors in development and disease
Tim E. Cawston et al.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2006)
Osteoarthritis: Pathobiology-targets and ways for therapeutic intervention
T. Aigner et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
Osteoarthritis cartilage histopathology: grading and staging
KPH Pritzker et al.
OSTEOARTHRITIS AND CARTILAGE (2006)
Osteoarthritis development in novel experimental mouse models induced by knee joint instability
S Kamekura et al.
OSTEOARTHRITIS AND CARTILAGE (2005)
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1α
S Nemoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with Osteoarthritis in mice
L Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
S Nemoto et al.
SCIENCE (2004)
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
F Picard et al.
NATURE (2004)
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
F Yeung et al.
EMBO JOURNAL (2004)
Role of NF-κB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals
S Agarwal et al.
ARTHRITIS AND RHEUMATISM (2004)
The mammalian SIR2 alpha protein has a role in embryogenesis and gametogenesis
MW McBurney et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)
Share Paper
