Journal
JOURNAL OF INFECTION
Volume 52, Issue 3, Pages 157-168Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.jinf.2005.09.001
Keywords
Staphylococcus aureus; MRSA; community-acquired; community-associated; community-onset; infection control; epidemiology; treatment
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Recently there have been reports indicating an increased incidence of MRSA infections, afflicting individuals with no apparent risk factors for hospital acquisition. Patients with comm unity-associated (CA) MRSA are significantly younger and had different distributions of clinical infections compared with HA-MRSA patients. CA-MRSA infections have mostly been associated with staphylococcal strains bearing the SCCmec type IV element and PVL genes. These strains are more frequently susceptible to a variety of non-beta-tactam antibiotics. Clinicians must be aware of the wide and, in some cases, unique spectrum of disease caused by CA-MRSA. Continued emergence of MRSA in the community is a public-heatth problem that warrants increased vigilance in the diagnosis and management of suspected and confirmed staphytococcal infections. (c) 2005 The British Infection Society. Published by Elsevier Ltd. All rights reserved.
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