Journal
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Volume 21, Issue 3, Pages 622-623Publisher
WILEY
DOI: 10.1111/j.1440-1746.2006.03418.x
Keywords
autoimmune thrombocytopenia; chronic hepatitis C; interferon; ribavirin
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Interferon-induced, immune-mediated, thrombocytopenia is a rare event. In this report the case is described of development of severe, reversible, autoimmune thrombocytopenia in a patient with chronic hepatitis C virus infection, 6 months after the discontinuation of pegylated interferon-alpha-2b plus ribavirin treatment. Physicians must be aware that autoimmune thrombocytopenia can occur even after the end of treatment, as a late onset complication, especially when using the pegylated forms of interferons, which have longer half-lives and prolonged activity.
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