Journal
QUIMICA NOVA
Volume 29, Issue 2, Pages 300-309Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0100-40422006000200022
Keywords
monolithic stationary phases; high performance liquid chromatography; capillary electrochromatography
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Monolithic stationary phases represent a new generation of chromatographic separation media. These phases consist of a continuous separation bed prepared by in situ polymerization or consolidation inside the column tubing. In recent years, their simple preparation procedure, unique properties and excellent performance have attracted quite remarkable attention in liquid chromatography and capillary electrochromatography. This review summarizes the preparation, characterization and applications of monolithic stationary phases. The analytical potential of these columns is demonstrated with separations involving various families of compounds in different separation modes.
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