Journal
NATURE REVIEWS CANCER
Volume 6, Issue 3, Pages 240-248Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc1820
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Funding
- NCATS NIH HHS [UH3 TR000943] Funding Source: Medline
- NCI NIH HHS [P50 CA083639, R01 CA109298, R01 CA109298-01A1, R01 CA110793, P50 CA083639-02, R01 CA110793-01] Funding Source: Medline
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Epidemiological studies indicate that stress, chronic depression and lack of social support might serve as risk factors for cancer development and progression. Recent cellular and molecular studies have identified biological processes that could potentially mediate such effects. This review integrates clinical, cellular and molecular studies to provide a mechanistic understanding of the interface between biological and behavioural influences in cancer, and identifies novel behavioural or pharmacological interventions that might help improve cancer outcomes.
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