Journal
JOURNAL OF ANTIBIOTICS
Volume 59, Issue 3, Pages 193-195Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2006.28
Keywords
pterocidin; Streptomyces; cytotoxic; delta-lactone
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A new cytotoxic compound, pterocidin, was isolated from the endophytic Streptomyces hygroscopicus TP-A0451, and the structure was determined on the basis of spectroscopic data. Pterocidin showed cytotoxicity against some human cancer cell lines with IC50 values of 2.9 similar to 7.1 mu M.
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