4.5 Article Proceedings Paper

Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics

Journal

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Volume 1758, Issue 3, Pages 404-412

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbamem.2005.10.008

Keywords

carbon nanotube; vector; vaccine; gene; drug delivery; peptide

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Functionalized carbon nanotubes (f-CNT) are emerging as a new family of nanovectors for the delivery of different types of therapeutic molecules. The application of CNT in the field of carrier-mediated delivery has become possible after the recent discovery of their capacity to penetrate into the cells. CNT can be loaded with active molecules by forming stable covalent bonds or supramolecular assemblies based on noncovalent interactions. Once the cargos are carried into various cells, tissues and organs they are able to express their biological function. In this review, we will describe the potential of f-CNT to deliver different types of therapeutic molecules. (c) 2005 Elsevier B.V. All rights reserved.

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