Journal
INFECTION GENETICS AND EVOLUTION
Volume 6, Issue 2, Pages 147-153Publisher
ELSEVIER
DOI: 10.1016/j.meegid.2005.04.003
Keywords
Trypanosoma brucei gambiense; sleeping sickness resurgence; wild animal reservoir; KIVI; PCR
Categories
Ask authors/readers for more resources
In order to Study the existence of a wild animal reservoir for Trypanosoma brucei gambiense in South Cameroon, blood was collected from wild animals in three human African trypanosomiasis foci and from a nonendemic control area. The 1142 wild animals sampled belonged to 36 different species pertaining to eight orders (407 primates, 347 artiodactyls, 265 rodents, 54 pangolins, 53 carnivores, 11 Saurians and crocodilians, and five hyraxes). QBC (R) and KIVI tests detected trypanosomes on 1.7% (13/762) and 18.4% (43/234) of: animals examined, respectively. Using specific primers, T brucei non-gambiense group 1 DNA was detected on 56 animals (4.9%). This infection rate was 5.3% in the endemic zone and 3.8% in the control zone. Of the 832 animals of the endemic zone, PCR revealed T. b. gambiense group I DNA in 18 (2.2%). These hosts included two rodents, two artiodactyls, two carnivores and two primates. T b. gambiense group 1 was absent from animals from the nonendemic zone. A decrease in the prevalence of T b. gambiense group 1 was observed in wild animals from the Bipindi sleeping sickness focus after a medical survey and vector control in this area. The epidemiological implication,,; of these findings remain to be determined with further investigations. (c) 2005 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available