4.4 Article

Positive selection can create false hotspots of recombination

Journal

GENETICS
Volume 172, Issue 3, Pages 2011-2014

Publisher

GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.105.052183

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Simulations of positive directional selection, under parameter values appropriate for approximating human genetic diversity and rates of recombination, reveal that the effects of strong selective sweeps on patterns of linkage disequilibrium (LD) mimic the pattern expected with recombinant hotspots.

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