4.3 Article

The visual evoked potential in the mouse - Origins and response characteristics

Journal

VISION RESEARCH
Volume 46, Issue 6-7, Pages 902-913

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.visres.2005.09.006

Keywords

electroretinogram; visual evoked potential; mouse; temporal; spatial; sweep; acuity; electrophysiology

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The visual evoked potential (VEP) in the mouse is characterized and compared to responses obtained with the electroretinogram (ERG). The results indicate that: 1, the VEP originates in the visual cortex; 2, the rod and cone pathways contribute separately to the VEP; 3, temporal tuning functions for rod and cone ERGs are low pass and band pass, respectively; VEP tuning functions are both band pass; and 4, VEP acuity is 0.62 +/- 0.156 cycles/degree. The differences in the spatial and temporal tuning functions obtained from the retina and visual cortex provides a tool to investigate signal processing through the visual system. (c) 2005 Elsevier Ltd. All rights reserved.

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